Thursday, August 27, 2020

F.D.R. essays

F.D.R. expositions Thinking back on Depression-period America and its two most conspicuous pioneers, it is basic that neither one of the ones be portrayed exclusively as an extraordinary liberal or outrageous traditionalist. Or maybe, if the activities and accomplishments of every pioneer are seen with a fair eye, one will see that Roosevelt was fundamentally a liberal with the essential bit of conservatism, and Hoover was principally a traditionalist with a slight piece of radicalism. Understand that the timespan both Herbert Hoover and Franklin D. Roosevelt managed was one which comprised of grave financial strife and far reaching destitution for the American individuals brought about by a pack of interior and outer variables, some of which couldve been helped by phenomenal authority. It is a direct result of the colossally troublesome issues America was encountering at the time that looking back such examination is set upon the intentions and political ways of thinking held by both FDR and Herbert Hoover. To discover how and a why a pioneer responds to affliction when his nation needs him most may maybe demonstrate the value and significance of that pioneer. Verification of Herbert Hoovers status as a firm preservationist lies in the way that he kept up a solid determination to hold fast to conventional techniques for reestablishing the economy during the Depression. In archive B, Hoover explains his arrangement and viewpoint for managing the desperate financial circumstance. Generally speaking, Hoover separations himself from promising to roll out any intense improvements. He censures the utilization of crisis authoritative or official activity as a methods by which to diminish the Depressions side effects. Regularly alluded to as a tough maverick, Hoover was resolved to utilize the set up training of free undertaking and genuinely uninhibited private enterprise to recapture thriving in the U.S. since these strategies functioned admirably previously. It was his immovable confidence in free endeavor that disheartened hello... <!

Saturday, August 22, 2020

Physics paper Essay Example | Topics and Well Written Essays - 1000 words - 1

Material science paper - Essay Example Another region of research will decide the distinctive among obstruction and momentum. The unmistakable properties of opposition and flow will be considered so as to recognize different sorts of obstruction in conduits of power. Resistivity and conductivity are likewise concentrated in this examination; the variables which impact the conductivity for examples temperatures are additionally option to investigating different sorts of uses which has high opposition and flow utilization the information on electric age will be included (S. Knight). For additional comprehension of obstruction and flow, an examination is acted in the research center so as to break down the impacts of opposition and ebb and flow in power transmission. The accompanying contraption and materials required while doing the investigation (S. Knight). In the above set up, while the electrons are going through meager metal fiber of the light, the electrons face more resistance on the grounds that the fiber is more slender when contrasted with the wire utilized in the test. The resistance to electric flow relies upon the sort of material, cross-sectional territory and its temperatures (Jeong). Fundamentally it tends to be said the conductors have low obstruction while separators have low opposition. The obstruction lessens measure of current through the circuit and the bulb will shine contingent upon the measure of electrons going through the wire. At the point when electrons are moving against a similar course it causes contact, this is showed in type of a similar time the readings of ammeter changes. The centralization of warmth in fiber will compel the bulb to shine. In the instances of short out, the bulb will quit gleaming in light of the fact that there is no finished progression of electrons. There will be any opposition on the grounds that the circuit is fragmented. At the point when we go through batteries in the above set, the battery will run low on the charge in light of the fact that the

Friday, August 21, 2020

Us Confederation Essays - United States, , Term Papers

Us Confederation The Articles of confederation were endorsed in 1781 and turned into the primary constitution if the United States of America. It gave a solid national government to make all expresses a solitary country. The articles made a firm class of kinship, the articles had a national congress which comprised of two to seven representatives. The representatives were from each state and were accountable for outside relations proclaiming war, harmony, armed force and naval force matters, issues, mandates and to pass laws. The main issue was they couldn't uphold them. The articles precluded congress the force from securing tax assessment a genuine oversight in time of war. The national government could get reserves just by approaching states for commitments called orders, yet on the off chance that a state neglected to participate which many did, congress approached everything with no budgetary help. Two great bits of enactment came out of the free sew confederation. The first was the land law of 1785. It set up the manner in which land was possessed by the government. That wherein was fundamentally the domain won from Britain that wasnt guaranteed by one of the states, and could be isolated and sold. It called for townships to be partitioned into one square mile, or 640 sections of land, and sold at an open sale. Some portion of the income went to the foundation of state funded schools. The second was known as the Northwest law, in 1787. It expressed that as new states were admitted to the nation, they would be equivalent inside and out to the first thirteen. It additionally restricted subjugation in the new domains, despite the fact that this was later to be changed. The two laws were acceptable beginnings to settling the new nation. Be that as it may, continuous difficulties in attempting to manage trade between the states and in attempting to fund-raise for the government despite everything tormented the country, particularly since each state had its own cash and doled out it its own worth. With everything taken into account, I feel that the articles of confederation was made to give the individuals a greater amount of an authority over the legislature and it was an endeavor to let the individuals make their own guidelines, not the same as Britain. History

Tuesday, May 26, 2020

French Expressions Using Prendre - to Take

The irregular French verb prendre means to take and is also used in many idiomatic expressions. This  flexible irregular French -re verb  has a specific way to use it. Watch out for the Sexual Meaning of Prendre We hope not to offend anybody here but it’s a mistake we often hear and that can be quite embarrassing in French. Prendre used with a person has a sexual meaning, just like take has in English.So, do say:Il m’a emmenà ©e au cinà ©ma he took me to the theaterIl est passà © me prendre à   midi He picked me up at noonbut don’t sayIl m’a prise dans sa voiture - he took me in his car - which definitely has another meaning in French. You need amener/emmener here. Say Prendre Une Dcision (Not Faire) We say to take a decision, we don’t use make (faire). It’s a mistake you’ll also hear French people make in English.Ce n’est pas toujours facile de prendre une dà ©cision.It’s not always easy to make a decision. Expressions With Prendre Etre prisTo be tied up/busyJe ne peux pas venir samedi, je suis dà ©jà   prise.I can’t come on Saturday, I already have plans. Passer prendre quelquunTo go pick someone upTu peux passer me prendre vers midi ?Can you come get me around noon? Prendre à   gauche/droiteTo turn left/rightAprà ¨s le feu, tu prends à   droite.After the signal, take a right. Prendre un pot/ un verre (informal)To have a drinkTu veux prendre un pot samedi soir?Would you like to have a drink Saturday night? Prendre lairTo get a breath of fresh air/take a strollJ’aime bien prendre l’air vers sept heures.I enjoy going for a stroll around 7 PM. Prendre bien la choseto take something wellQuand il m’a dit qu’il ne viendrait pas, je l’ai trà ¨s mal pris.When he told me he wouldn’t come, I didn’t take it well. Prendre leauto leak; to founderMon sac à ©tanche prend l’eau.My waterproof bag leaks. Prendre feuTo catch fireAprà ¨s l’accident, la voiture a pris feu.After the accident, the car caught on fire. Prendre fin (formal)To come to an endLe film prend fin.The movie is coming to an end. Prendre froidTo catch a coldTu devrais mettre un pull, tu vas prendre froid.You should put a sweater on, you’re going to catch a cold. Prendre garde (formal)To be careful, watch outAttention ! Prenez garde à   vous !Careful ! Be cautious ! Prendre goà »t à   quelquun/ quelque chose (formal)To take a liking to someone / somethingFinalement, j’aime bien jouer au tennis. J’ai mis le temps, mais j’y ai pris goà »t.At the end, I like playing tennis. It took me some time but it grew onto me. Prendre la mer (very old fashion)To set sail, to put out to seaLe bateau a pris la mer en juin.The boat set sail in June. Prendre au pied de la lettreTo take literallyNe prends pas tout au pied de la lettre !Don’t take everything so literally. Prendre du poidsTo gain weightÀ Noà «l, je prends toujours du poids.At Christmas time, I always gain weight. Prendre quelquun la main dans le sacto catch someone red-handedJ’ai pris mon fils la main dans le sac.I caught my son red-handed. Prendre rendez-vous avecTo make an appointment withJe voudrais prendre rendez-vous avec le directeur.I’d like to make an appointment with the director. Prendre sa retraiteTo retire (from work)Il va prendre sa retraite l’annà ©e prochaine.He is going to retire next year. Prendre ses jambes à   son couto run offQuand la police est arrivà ©e, le voleur a pris ses jambes à   son cou.When the police arrived, the thief ran away. Prendre son courage à   deux mainsto get up ones courageJ’ai pris mon courage à   deux mains et je lui ai tout dit.I gathered up my courage and told her everything. Quest-ce qui ta pris ?Whats gotten into you?Pourquoi tu as pleurà © soudainement ? Qu’est-ce qui t’a pris ?Why did you suddenly cried? What’s gotten into you? Se prendre (pour)to consider oneself (as)Mais, elle se prend pour qui cette fille?but, who does she think she is, that girl? Sen prendre à   quelquunto pick on someone, lay into someone (could be physical, mental, light or serious)Quand il est en colà ¨re, il s’en prend toujours à   sa femme.When he is angry, he always picks at his wife. Sy prendreto go about doing somethingComment tu t’y prends pour ne jamais te faire prendre ?How do you go about it to never get caught? Sy prendre comme un piedto have a wrong way to do something, to do a poor job.Ce n’est pas comme à §a qu’on dà ©coupe un poulet. Tu t’y prends comme un pied.That’s not the way to cut a chicken. You’re doing a very poor job.

Friday, May 15, 2020

Review of Anti-angiogenic Therapy in Breast Cancer - Free Essay Example

Sample details Pages: 3 Words: 872 Downloads: 5 Date added: 2019/02/06 Category Medicine Essay Level High school Tags: Breast Cancer Essay Did you like this example? Abstract Tumors need sustained blood and nutrition supply in their growth and achieved by vascular endothelial growth factor(VEGF) families, so the anti-angiogenic therapy(AAGT), which aims at stopping the VEGF route to inhibit the overexpression of VEGF ligand family, have huge potential in curing tumors. But in breast cancer treatment, this kind of treatment did not show great efficiency and efficacy, that means AAGT is not as good as scientists believed initially. But there still be great potential to improve this therapy by combining to other treatment like chemotherapy or gene-target therapy to inhibit its toxicity and tumor cell resistance.. Don’t waste time! Our writers will create an original "Review of Anti-angiogenic Therapy in Breast Cancer" essay for you Create order Introduction This opinion paper helps to understand the mechanism of anti-angiogenic therapy(AAGT), its promises, and pitfalls surrounding usage of breast cancer, discuss the present perspective, and explore future direction of both applications of AAGT and treatment of breast cancer. Tumor growth needs a sustained purveyance of nutrients including oxygen to maintain the expansive proliferation of tumor cells. Therefore, the tumor could induce the germination of new vessels from the surrounding vascular [fig1]with several types of cytokines and growth factors especially VEGF-A. Plus, VEGF usually over-express in most solid cancers [1]. Plus, several preclinical research shows that inhibition VEGF works in animal models for suppressing tumor growth[2,3]. Therefore, inhibition of sprouting angiogenesis by blocking the VEGF signaling pathway exists in suppressing tumor in human beings. (Fig 2) [1]. Breast cancer is a malignant tumor arising from the cells of the breast, which is the most common cancer among American women. Breast cancer has more than five different types, including Ductal carcinoma in situ, Invasive ductal carcinoma, Invasive lobular carcinoma and some other much less in common ones[4]. In breast cancer, the level of angiogenesis is relevant to survival, that is, high levels of VEGF and other angiogenic factors indicate high-risk disease correlating with a poor prognosis.[5] Search strategy I gained all the information from current years’ journal paper in both AAGT and breast cancer treatment. Went through those data, analyzed all information provided in recent journals, discussed both advantage and disadvantage of this therapy and came out with the personal presentation of the future usage of AAGT and breast cancer treatment as well. Discussion According to those literatures, I could get the conclusion that 1) the basic mechanism of tumor vessels is thinner the wall of vessel cell owing to lacking pricytes, this diminish changed the permeability within both same and different tumors[6], that abnormal vascularity could increase the tumor resistant to chemotherapeutic agents; 2) VEGF inhibitors cannot provide long-lasting clinical response in all patients [7], where the VEGF-target therapy resistance could be explained with two mechanisms: tumor will not respond with an outset of treatment, that is, they have intrinsic resistance, or they do respond the treatment at very beginning, but receiving the ability to withstand treatment during growth, which means they developed the acquired resistance[8]. preclinical tests also show that VEGF- target therapy has less effective stopping the establishment of tumor vessels[9].3)in breast cancer part, Phase 3 clinical trials of VEGF routes inhibitors shows partially sensitive answered in AAGT[10] this conclusion could be verified by randomized trials in breast cancer, including four agents: metastatic 1st line, metastatic 2nd line and beyond, adjuvant and neo-adjuvant.[1] studies show that there is no significant improvement in overall survival(OS) and partially improved the progression-free survival(PFS), Bear HD et al.[11] and von Minckwitz G et al.[12] found that Doxorubicin/docetaxel/ cyclophosphamide  ±bevacizumab and Epirubicin/docetaxel/Cyclophosphamide  ± bevacizumab ) treatment in HER-2 negative population can improve the complete response rate in pathology at the primary endpoint. From what have been showed before, we can see that the AAGT does not works as effectively as we thought initially. But we can also find out that single agent given treatments are all failed, but the joint of the addition of bevacizumab agent to chemotherapy in HER2-negative transferred breast cancer(AVADO, RIBBON-1, and RIBBON-2) showed no improvement in OS, but PFS does, than chemotherapy[1]. It results from the limitations of AAGT showed in fig 3[13]. And these failures and limitation give us a new direction of anti-angiogenic remedy in breast cancer rather than laying into the non-effective situation at present. On the other hand, in the last ten years, HER2-directed therapy has already been a mature remedy of curing HER-2-positive breast cancer which is the most common type. And new delivery of chemotherapeutic agent choosing such as monoclonal antibodies, small molecule inhibitors, and antibody-drug conjugates are also an aspect of improving the efficacy and effectiveness of drugs no matter in which type of treatment including AAGT. Future direction By addition to some herbal medicine or other kinds of drugs, AAGT may also show the huge potential in curing breast cancer[14] in the future, for reducing the toxicity and resistance of present drugs. In my opinion, even the AAGT shows almost nothing in present preclinical trials, and some studies found herbal medicine could help reduce the toxicity during the treatment, Chinese traditional treatment including traditional Chinese medicine, acupuncture etc could be used as an Adjuvant, or the combination of chemotherapy, that is, all the limitation could help to search the really useful and effective treatment not only in breast cancer but also changing AAGT into an available, operative and profitable remedy.

Wednesday, May 6, 2020

Human Memory Recognition And The Dual Process Model

Recognition memory is a particular aspect of explicit memory which enables one to correctly determine whether a stimulus has been previously encountered. A much debated question is how human memory recognition operates. Generally, there have been two dominant approaches which have attempted to elucidate recognition memory; these include the single-process theory and the dual-process theory. The single process models were initially based on the signal detection theory (SDT); arguing that familiarity and recollection are based upon a single process continuum that represent weak (familiarity) and strong (recollection) memories (Reder, Arndt Park, 2006). However, the dual process models have gained additional supporting evidence claiming that recognition is not founded along a single continuum; but founded on two distinct processes: recollection and familiarity (Reder et al., 2006). Respectively, recognition and familiarity are sometimes referred to as ‘remember’ and †˜know† or the remember/know paradigm. The remember/know paradigm was initially introduced by Tulving (1985), to investigate the hypothetical conscious awareness that accompanies memory retrieval (Dunn, 2001). The dual process view postulates that recollection and familiarity are identified as independent processes. It is a widely held view that recollection typically demonstrates the retrieval of contextual information regarding a particular study episode, for instance this qualitative information could beShow MoreRelated Learning Styles and the Brain1645 Words   |  7 Pagescontexts, learning style lies at the foundation of individual identity and development. 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In th is paper, we have discussed a brief overview of offline signature verification techniquesRead MoreWorking Memory5992 Words   |  24 Pagesï » ¿Working Memory ââ€"  Working memory enables us to keep things in mind for short periods (215 seconds) as we think, e.g. while reading, making a list etc. ââ€"  It s related to but different to short-term-memory (STM) and long-term-memory (LTM). ââ€"  Chapter focuses on Baddley s (1986) model of phonological working memory, vocabulary acquisition and computational modelling of working-memory. ââ€"  The concept of span means how many items from a briefly presented set can be remembered, e.g. word spanRead Moreevaluation of the WMM2112 Words   |  9 Pagesï » ¿CEP – Evaluation of the Working Memory Model Atkinson’s and Shiffrin’s (1968) multi-store model was extremely successful in terms of the amount of research it generated. However, as a result of this research, it became apparent that there were a number of problems with their ideas concerning the characteristics of short-term memory. Building on this research, Baddeley and Hitch (1974) developed an alternative model of short-term memory which they called working memory. Baddeley and Hitch (1974) arguedRead MoreThe Theory Of Perception And Knowing1760 Words   |  8 Pages This â€Å"inferential leap† becomes even more complex when applied to the social world. In a similar vein, Bruner posited that sensory information is given meaning based on prior percepts. Even the immediate recognition of an object, known as phenomenal immediacy, entails a categori-zation process that operates on an unconscious level. Use of meaning in making inferences was a fundamental component of Gestalt psy-chology. 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Introduction In this essay I will outline the main theoretical models relating to loss and grief. I will show how these theories may support individuals within the counselling process. To demonstrate the above I will draw upon my experience

Tuesday, May 5, 2020

Nutrition Science Common Foods Booklet

Questions: 1. Find the Dietary Reference Intakes for protein, iron, calcium, and vitamin A. Then, determine how much of each nutrient was consumed by calculating the total amount of protein, iron, calcium, and vitamin A in the above given day. Which nutrients are higher than the recommendations? Lower than the recommendations? 2. Determine the total number of servings from each food group was actually eaten for the given day. Compare this to what is recommended in Canadas Food Guide to Healthy Eating for a man of Marcos age. Which food groups are in higher amounts than recommended? Which are lower? 3. What is your overall impression of the diet analysis you performed? Should your character be concerned? Why or why not? What are the possible health consequences if your character continues to follow his/her current eating pattern? Make a few specific recommendations that can simultaneously improve the food groups and the nutrient intake for your character. Answers: 1. According to the Canadas dietary reference intakes, the recommended values for protein, iron, calcium, and vitamin A are: Protein= 60gms Iron= 14mgs Calcium= 1000mgs Vitamin A= 900g/day PROTEIN From Marcos diet diary, each nutrient amount could be calculated for a given day. Marco consumed 120g broiled haddock, which contains majority of the protein. 4oz of broiled haddock contains 21.43g of protein. 1 cup (250 ml) 2% milk contains 8.3g. 2 plain pancakes contain 4.26g. cup (125 ml) vanilla ice cream contains 3.5g. 1 cup (250 ml) cream style corn contains 4.5g. cup (125 ml) peas and carrots contain 3g of proteins. Hence, total protein consumption in a day for Macro is almost 45gms, which indicates that protein consumption is lower than the recommendations ("Eating Well with Canada's Food Guide - Main Page - Health Canada"). IRON 2 plain pancakes contain 1.2mgs of iron. 3 tablespoons (45 ml) maple syrup contains 3.6mgs. grapefruit contains 0.1mg. 1 almond butter sandwich contains 4mg. 2 stalks celery contains 0.2mg of iron. 4 oz (120 g) broiled haddock contains 0.3mg. 1 cup (250 ml) cream style corn contains 1mg. cup (125 ml) peas and carrots contain 0.9mg. 12 oz. can of cola contain 0.4mg. Hence, it could be calculated from the diet that total iron consumption in a day for Macro is almost 12mgs, which is less than the recommended intake. CALCIUM Marco consumed 1 cup (250 ml) 2% milk, which contains majority of the calcium in his days diet. 1 cup (250 ml) 2% milk contains 300mgs of calcium. 2 plain pancakes contain 116mg. 45 ml maple syrup contains 63mg. grapefruit contains 27mg. 1 almond butter sandwich contains 74mg. 2 stalks celery contain 50mg of calcium. Twice consumption of 12oz of cola contains 14.8mg. 2 chocolate chip cookies contain 6.2mg. 120 g broiled haddock contains 120mg. 250 ml cream style corn contains 1mg. 125 ml peas and carrots contain 23mg. So, it could be calculated from the diet that total calcium consumption in a day for Macro is almost 800mgs. However, the recommended consumption is 1000mg, which indicates lower calcium consumption than the recommendations. VITAMIN A grapefruit contains almost 424 g. 250 ml 2% milk contains almost 138 g. 1 almond butter sandwich contains almost .54 g. 2 stalks celery contains 86.10 g. 120 g broiled haddock contains 17 g. 250ml cream style corn contains 57 g. 125 ml peas and carrots contain 2880 g. 125 ml vanilla ice cream contains 127 g. So, it could be calculated from the diet that total vitamin A consumption in a day for Macro is almost more than 3000 g that indicates higher consumption of vitamin A than recommended daily intake (Sizer, Whitney and Kicklighter). 2. The total number of servings from each food group that was actually eaten for the given day: Legumes and vegetables, Fruit: minimum one orange and dark green vegetable. Marco consumed grapefruit, 2 stalks celery, cup peas and carrots, 1cup cream style corn, Cereal: 2 slices whole wheat bread, 2 plain pancakes Fish: 4 oz broiled haddock Milk: twice 250 ml 2% milk, cup vanilla ice cream Recommended servings per day as per the Canadas Food Guide to Healthy Eating for a man of Marcos age: Legumes and vegetables: 8-10 Fruit: 8-10 Cereal: 8 Fish: 3 Milk: 2 From the comparison, it could be mentioned that his milk intake was accurate. His fruit consumption should be increased. No water intake has been mentioned but he should cut down calorie-rich drink like cola (Flora, Gupta and Tiwari). He consumed meat alternatives like beans, which is recommended by the guide. Macro had 2 slices whole wheat bread, which is beneficial ("Nutrient Value of Some Common Foods Booklet - Health Canada"). 3. The calculations would enable to provide an impression of Macros diet and from the analysis it could be mentioned that the character need to be concerned. This is because his protein, iron and calcium consumption is lower than the recommendation ("Dietary Reference Intakes"). However, his diet was rich in vitamin A. If he continues to follow his current eating pattern, he might develop various health consequences. Constant consumption of excessive vitamin A may cause skin discoloration, bone pain and liver damage (Taylor et al.). Simultaneously, low protein in diet may increase physical weakness and lack of calcium affects the bones to a major extent and cause osteomalacia and osteoporosis (Haugen and Musser). Iron deficiency may also give rise to fatigue, breathing shortness, skin paleness and so on (Goodnough). Marco should be recommended to have protein, calcium and iron rich diet. Though Marco included all types of food groups in his diet, he should focus on the number of serv ings per day to maintain a balanced diet. References "Dietary Reference Intakes" N.p., 2016. Web. 3 Nov. 2016. "Eating Well With Canada's Food Guide - Main Page - Health Canada" N.p., 2016. Web. 3 Nov. 2016. Flora, Gagan, Deepesh Gupta, and Archana Tiwari. "Toxicity Of Lead: A Review With Recent Updates".Interdisciplinary Toxicology5.2 (2012): n. pag. Web. Goodnough, Lawrence Tim. "Iron Deficiency Syndromes And Iron-Restricted Erythropoiesis (CME)".Transfusion52.7 (2011): 1584-1592. Web. Haugen, David M and Susan Musser.Nutrition. Detroit: Greenhaven Press/Gale Cengage Learning, 2012. Print. "Nutrient Value Of Some Common Foods Booklet - Health Canada" N.p., 2016. Web. 3 Nov. 2016. Sizer, Frances, Ellie Whitney, and Jana R Kicklighter.Nutrition. Belmont, Calif.: Wadsworth, Cengage Learning, 2014. Print. Taylor, Pennie J et al. "A Review Of The Nature And Effectiveness Of Nutrition Interventions In Adult Males A Guide For Intervention Strategies".Int J Behav Nutr Phys Act10.1 (2013): 13. Web.